PROFESSIONAL AESTHETIC EQUIPMENT
Clinical Research & Evidence Library
For Canadian Clinics & Medspas
Every device in DermaSpark’s portfolio is chosen through the same process: we review the clinical evidence before we ever bring a device to market. This library exists so that you can do the same.
Here you’ll find links to peer-reviewed studies, clinical trials, and published research for each piece of equipment we distribute. Whether you’re building a business case, satisfying a compliance requirement, or doing your due diligence, the science is organized by device.
All equipment sold by DermaSpark is licensed by Health Canada and CSA-approved. The research below reflects the clinical standards we hold ourselves and our partners to.
Health Canada Licensed
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Peer-Reviewed / Published Research
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Alpha Laser
A Paradigm Shift Towards Intelligent, Biologically Adaptive Diode Laser Hair Removal
This large-scale retrospective study spans more than 4 years, involving 338 sites across France, 45,467 patients, and approximately 200,000 laser hair removal sessions with the Alpha system. This study shows that under real-world operational settings, Alpha's adaptive biology approach provides personalized, safer, and more effective hair removal treatments that produce long-term results with up to 33% fewer sessions per patient.
Integrated Acne Management Using the Alpha System 3D IPL 430nm Applicator in Combination with Professional Topical Dermocosmetics
Alpha Clinical Research (MR19131-A) – 2026
This case series demonstrates that the combined use of the Alpha System 430 nm 3D IPL with an adjunctive cosmeceutical regimen resulted in rapid and consistent clinical improvement in inflammatory acne vulgaris under real-world conditions, and without significant adverse effects for patients.
Case Studies Compilation — Clinical Outcomes Across Multiple Modalities
Alpha Clinical Publications – 2025
This compiled case series presents real-world clinical outcomes across multiple Alpha System modalities, including IPL, diode laser, and combination treatments. Cases span a range of skin types and indications, illustrating protocol flexibility and the system's adaptability across diverse patient populations.
3D IPL Photo Rejuvenation and Pigmentation Protocol
Alpha Clinical Publication – 2023
This protocol document evaluates the clinical application of 3D IPL technology for photo rejuvenation and the reduction of pigmentation irregularities. Results demonstrate measurable improvement in skin tone uniformity and the reduction of solar lentigines after a standardized multi-session treatment course.
Canadian hair removal case study – preliminary result with the Alpha System using LLD laser Diode, 3rd generation POWER MOTION™
Alpha Internal Clinical Trial (Dr. Nadav) – 2023
This internal clinical trial aims to assess the preliminary safety and clinical efficacy of hair removal using the third-generation POWER-MOTION™ LLD 808nm non-invasive diode laser applicator. This case study highlights the Alpha system with the third-generation POWER-MOTION™ LLD Diode laser 808nm applicator as a safe and effective hair removal solution for patients with Fitzpatrick skin types I to III.
Lichtkraft Strahlend Schön: German Clinical Experience with SparkPro 3D IPL 530 nm for Tight & Bright Skin Outcomes
Alpha Clinical Case Study – 2023
Documenting clinical experience from a German aesthetic practice, this case study evaluates the SparkPro 3D IPL at 530 nm for combined skin tightening and brightening outcomes. Patients showed improvement in skin luminosity, pore appearance, and superficial pigmentation after a defined multi-session protocol.
Male Hair Removal with the Alpha System Featuring 3rd Generation POWER-MOTION™ LLD Diode Laser
Alpha Clinical Case Study (MR19218-1) – 2023
This case study documents the use of the third-generation POWER-MOTION™ diode laser in male patients seeking body hair removal. The POWER-MOTION™ technique enabled faster treatment coverage and higher pulse repetition rates, producing effective clearance with patient-reported comfort levels comparable to female treatment cohorts.
One-Year Follow-Up Hair Removal Study with the Alpha System Using ALD Laser Diode: Split-Body Comparison — 3rd Generation POWER-MOTION™ vs. 1st Generation Stamping Mode
Alpha Clinical Research (MR19209) – 2023
This split-body study followed patients for one year post-treatment, comparing 3rd generation POWER-MOTION™ outcomes against 1st generation stamping on contralateral body sites. Long-term hair clearance was superior in the POWER-MOTION™ arm, with faster treatment delivery and comparable safety across both techniques.
The Synergistic and Complementary Action of Polychromatic IPL 590–1100 nm in Combination with the 808 nm Diode Laser in Managing Miniaturisation of Facial Hair
Alpha Clinical Research – 2023
This study examined a combined treatment protocol using broadband IPL (590–1100 nm) alongside the 808 nm diode laser for patients experiencing facial hair miniaturisation — a condition where hairs become finer and harder to target effectively. The combination approach proved more effective than either modality alone in halting miniaturisation and reducing hair density.
3D Pulse Technology and the Importance of Temperature Control
Alpha Technical White Paper – 2022
This white paper examines the role of precise thermal management in third-generation 3D IPL pulse delivery. Findings indicate that real-time temperature control significantly reduces the risk of epidermal injury while maintaining the fluence levels required for effective chromophore targeting.
Alpha System 3D IPL S-430 Treatment for Acne Vulgaris
Alpha Clinical Research (MR19203-1) – 2022
This study assessed the clinical outcomes of repeated IPL S-430 sessions for the treatment of mild-to-moderate acne vulgaris. Inflammatory lesion counts decreased by a statistically significant margin across the treatment cohort, and patients reported improvements in skin texture and overall complexion quality at the 3-month follow-up.
Alpha System IPL S-530 Treatment for Rosacea and Facial Telangiectasia
Alpha Clinical Case Series (MR19202-1) – 2022
This case series documents patient outcomes following IPL S-530 treatment for diffuse facial redness and visible telangiectasia associated with rosacea. Practitioners recorded consistent vascular clearance and reduction in erythema across patients with moderate presentations, without significant adverse events.
Alpha System Single-Site Hair Removal Comparison Study: POWER-MOTION™ vs. Stamping Technique
Alpha Clinical Research (MR-19204) – 2022
This head-to-head comparison study evaluated the POWER-MOTION™ gliding technique against the traditional stamping method for hair removal at a single clinical site. POWER-MOTION™ demonstrated equivalent or superior hair reduction in significantly shorter treatment times, while patient discomfort scores favoured the dynamic delivery method.
Efficacy and Safety of Intense Pulsed Light Therapy for Unwanted Facial Hair: A Retrospective Analysis in Skin of Color
Peer-Reviewed Aesthetic Publication (Ajay Deshpande) – 2022
This retrospective analysis examined the use of IPL for facial hair reduction specifically in patients with Fitzpatrick skin types IV–VI. The study reported effective hair reduction with careful parameter selection and identified a protocol framework that minimizes hyperpigmentation risk in darker skin tones.
FineMotion™: A Paradigm Shift in Pulse-Modulated LLD/ALD 808 nm Diode Laser Treatment of Fine and Vellus Hair in Female Patients
Alpha Clinical Case Study (MR19130-1) – 2022
This case study evaluates the FineMotion™ technique for treating fine and vellus facial hair in female patients using an 808 nm diode laser. Results showed effective reduction of difficult-to-treat hair types with minimal discomfort, representing a meaningful advancement for patients previously considered poor candidates for laser hair removal.
Innovating Skin Care: The Alpha 3D IPL S-430 for Early Acne Intervention and Scar Prevention
Alpha Clinical Case Study (MR19126-A) – 2022
This case study evaluates early-stage acne treatment with the IPL S-430 as a scar prevention strategy. By targeting Propionibacterium acnes and reducing sebaceous activity at earlier stages of breakout, the protocol demonstrated a reduction in inflammatory lesion progression and secondary scarring outcomes.
IPL S-430 Acne Results in Asian Skin
Alpha Clinical Case Series – 2022
This case series documents the use of the IPL S-430 for acne treatment in Asian patients with Fitzpatrick skin types III–IV. Results indicated effective suppression of inflammatory acne with adapted fluence parameters, demonstrating that the S-430 can be applied safely in populations with higher melanin density when protocols are appropriately adjusted.
Laser-Based Precision Facial Hair Removal in Women Using the Alpha SparkPro 808 nm Diode Laser in Single-Stamping Mode
Alpha Clinical Case Study (MR19128-A) – 2022
This case study evaluates the single-stamping mode of the Alpha SparkPro 808 nm diode laser for precise removal of facial hair in female patients. The stamping technique allowed targeted treatment of individual follicles in sensitive facial regions, producing effective clearance with minimal erythema and high patient tolerance.
Unwanted Bikini Area Hair Removal in German Female Patients Treated with the ALPHA SparkPro System Using an 808 nm Diode Laser
Alpha Clinical Case Study (MR19129-A) – 2022
This case study reports outcomes for female patients undergoing bikini area hair removal using the ALPHA SparkPro 808 nm diode laser in a German clinical setting. Consistent hair reduction was achieved across sessions, with low rates of adverse events and strong patient satisfaction in a sensitive treatment zone.
Alleviating Skin Pigmentation Using 3D IPL: A Retrospective Study
Alpha Clinical Research – 2021
This retrospective analysis reviewed outcomes in patients treated for various pigmentation concerns using the 3D IPL platform. The study found a clinically significant reduction in melanin-based lesions across multiple Fitzpatrick skin types, with a favorable safety profile and high patient satisfaction scores.
Beyond Redness: Practical Rosacea Management with 590 nm 3D IPL, Targeted Topical Therapy, and Demodex-Guided Assessment
Alpha Clinical Case Study (MR17205-A) – 2021
This case study presents a multimodal protocol combining 590 nm 3D IPL with topical agents and Demodex mite assessment in rosacea management. The integrated approach produced superior outcomes to IPL monotherapy, including reduced inflammatory papules and prolonged remission periods.
Magma Clinical Study — Diode Laser Hair Removal
Alpha / Magma Clinical Publication – 2016
One of the foundational diode laser hair removal studies supporting the Alpha platform's lineage, this clinical study evaluated hair removal efficacy using Magma diode laser technology across a mixed patient cohort. Hair count reduction was significant at the 6-month follow-up, establishing baseline benchmarks that subsequent generations of the technology have continued to improve upon.
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Dermalux
Combined LED Wavelengths for Facial Hypervascularization
Photobiomodulation, Photomedicine, and Laser Surgery (P. Naranjo) – 2023
This peer-reviewed study assessed the use of multi-wavelength LED therapy in reducing facial hypervascularization and diffuse redness. The combined light protocol produced measurable reduction in vessel visibility and patient-reported flushing after a defined session series, with no adverse thermal effects on surrounding tissue.
Tri-Wave MD: Role of Photo-Biomodulation Therapy in Facial Rejuvenation and Facial Plastic Surgery
Photobiomodulation Clinical Paper — Dermalux – 2022
This paper presents the clinical evidence supporting the Tri-Wave MD protocol, which delivers simultaneous red, blue, and near-infrared LED wavelengths. Clinical outcomes documented include accelerated wound healing, reduction in post-procedure erythema, and significant improvement in skin texture across cosmetic and dermatological patient cohorts.
LED Photobiomodulation Therapy in the Management of Psoriasis
Clinical LED Research Publication – 2021
This clinical paper reviewed the application of photobiomodulation using LED light therapy in psoriasis management. Patients with plaque psoriasis showed reductions in lesion severity scores after regular LED sessions, offering a non-pharmacological adjunct that is well tolerated and free of the side effects associated with systemic treatments.
LED Technology in Aesthetic Medicine: A Technical Overview
Aesthetic Dermatology Clinical Review – 2020
This overview article surveys the evidence base for LED light therapy across a range of aesthetic dermatology applications, including wound healing, anti-ageing, acne, and skin rejuvenation. The paper reinforces the clinical rationale for multi-wavelength LED platforms and documents the mechanism by which targeted photons stimulate mitochondrial activity in skin cells.
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Dermaroller
Hair Growth Clinical Study Using Dermaroller Microneedling
Dermaroller Clinical Research – 2024
This clinical study evaluated the use of Dermaroller microneedling as a standalone and combination treatment for hair loss and scalp stimulation. Results demonstrated measurable improvement in hair density and follicle activation at the study endpoint, supporting microneedling as a viable adjunct in non-surgical hair restoration protocols.
Hair Growth Clinical Study Using Dermaroller Microneedling
Dermaroller Clinical Research – 2024
This clinical study evaluated the use of Dermaroller microneedling as a standalone and combination treatment for hair loss and scalp stimulation. Results demonstrated measurable improvement in hair density and follicle activation at the study endpoint, supporting microneedling as a viable adjunct in non-surgical hair restoration protocols.
Medical Studies Summary Booklet — Dermaroller Twist Microneedling
Dermaroller Clinical Evidence Compendium – 2023
This evidence compendium summarizes the body of peer-reviewed research supporting microneedling as a collagen induction therapy. Key findings across multiple studies confirm that controlled micro-injuries from the Twist Microneedling system stimulate neocollagenesis, improving skin laxity, scarring, and texture with minimal downtime.
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Divine Pro
Combination of OxyGeneo, TriPollar RF, and RF Microneedling for skin regeneration in Indonesian Females
Journal of Dermatology Research – 2025
This clinical study examines the safety and efficacy of a novel protocol combining Divine Pro RF Microneedling with non-invasive TriPollar RF therapy and Oxygeneo therapy for the rejuvenation of Asian female skin. Results demonstrate significant smoothing and tightening, with a more defined jawline and a clearer complexion, one month after protocol completion. The treatment was proven safe for Asian skin with greatly reduced downtime.
Microneedling With RF- Assisted Skin Penetration Improves the Hard- to- Treat Periorbital Wrinkles
This clinical study examines the safety and efficacy of VoluDerm RF Microneedling for the correction of periorbital wrinkles.The results demonstrated a statistically significant reduction in periorbital wrinkle severity, with an average 49% decrease of LFW score and improvements noted across all skin types. The treatment was well tolerated without anesthetics, with minimal downtime and few adverse events, which were transient and resolved without intervention.
Microneedling With RF- Assisted Skin Penetration Improves the Hard- to- Treat Periorbital Wrinkles
This clinical study examines the safety and efficacy of VoluDerm RF Microneedling for the correction of periorbital wrinkles.The results demonstrated a statistically significant reduction in periorbital wrinkle severity, with an average 49% decrease of LFW score and improvements noted across all skin types. The treatment was well tolerated without anesthetics, with minimal downtime and few adverse events, which were transient and resolved without intervention.
Therapeutic Combination of VoluDerm Radiofrequency Microneedling and Glycolic Acid Peel in Scaled-Up Concentrations
This clinical study examines the safety and efficacy of a novel rejuvenation protocol combining Divine Pro RF Microneedling with Glycolic Acid chemical peel. Clinical photography taken 6 months after the last treatment demonstrated improvement in elasticity, wrinkling, roughness, pigmentation, erythema, and pore size across the entire treated group. The treatments were well tolerated without preprocedural anesthesia. No serious or systemic events that would require therapy were identified.
Divine Pro – Fractional RF Technologies for Skin Rejuvenation
Divine Pro Technical White Paper – 2022
This white paper details the scientific basis of the Divine Pro platform's TriFractional RF microneedling system. By delivering radiofrequency energy at precise fractional depths via insulated microneedles, the device triggers controlled thermal remodelling of collagen and elastin while protecting the epidermis, producing measurable lifting and tightening outcomes with lower downtime than ablative alternatives.
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Divine Pro
Divine Pro – Fractional RF Technologies for Skin Rejuvenation
Divine Pro Technical White Paper – 2022
This white paper details the scientific basis of the Divine Pro platform's TriFractional RF microneedling system. By delivering radiofrequency energy at precise fractional depths via insulated microneedles, the device triggers controlled thermal remodelling of collagen and elastin while protecting the epidermis, producing measurable lifting and tightening outcomes with lower downtime than ablative alternatives.
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Geneo X
Hydration Effect of Geneo X Actions on Human Skin
QACS Laboratories Independent Testing – 2026
This independent laboratory study evaluated the moisturizing properties of different OxyGeneo treatments, with and without Tripollar RF. Results demonstrate significantly higher moisture levels after 6 treatments, with improved elasticity and reduced TEWL in all patients and all Oxypod treatments
Hydration Effect of Geneo X Actions on Human Skin
QACS Laboratories Independent Testing – 2026
This independent laboratory study evaluated the moisturizing properties of different OxyGeneo treatments, with and without Tripollar RF. Results demonstrate significantly higher moisture levels after 6 treatments, with improved elasticity and reduced TEWL in all patients and all Oxypod treatments
Combination of OxyGeneo, TriPollar RF, and RF Microneedling for skin regeneration in Indonesian Females
Journal of Dermatology Research – 2025
This clinical study examines the safety and efficacy of a novel protocol combining OxyGeneo therapy with non-invasive Tripollar RF therapy and Divine Pro RF Microneedling for the rejuvenation of Asian female skin. Results demonstrate significant smoothing and tightening, with a more defined jawline and a clearer complexion, one month after protocol completion. The treatment was proven safe for Asian skin with greatly reduced downtime.
OxyGeneo Treatment for Bacne (Back Acne): Clinical Test Results
OxyGeneo Clinical Testing – 2022
These clinical test results document the application of OxyGeneo technology to truncal acne (bacne) across a patient test group. Outcomes included reduction in active inflammatory lesions and improvement in post-acne discoloration on the back, extending the device's proven facial indications to a commonly underserved body treatment area.
Geneo OxyGeneo QACS Laboratories Efficacy Study
QACS Laboratories Independent Testing – 2020
This independent laboratory study evaluated the biological effect of the OxyGeneo Super Facial platform on skin oxygenation, hydration, and the delivery of active ingredients. Results validated the device's core Bohr Effect mechanism — whereby the skin responds to CO₂ application by increasing oxygen-rich blood flow to the surface — producing measurable increases in skin luminosity and ingredient absorption.
Geneo OxyGeneo QACS Laboratories Efficacy Study
QACS Laboratories Independent Testing – 2020
This independent laboratory study evaluated the biological effect of the OxyGeneo Super Facial platform on skin oxygenation, hydration, and the delivery of active ingredients. Results validated the device's core Bohr Effect mechanism — whereby the skin responds to CO₂ application by increasing oxygen-rich blood flow to the surface — producing measurable increases in skin luminosity and ingredient absorption.
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Helios III
Evaluating the Risk Factors of Post-Inflammatory Hyperpigmentation Complications with Nd:YAG Laser
Clinical Aesthetic Dermatology Publication – 2021
This study specifically investigated which patient and protocol factors increase the risk of post-inflammatory hyperpigmentation (PIH) following Nd:YAG laser treatment. Key risk predictors were identified including skin phototype, baseline pigmentation density, and cooling protocols — providing actionable parameters for safer treatment planning across diverse populations.
A Comparative Study of the Efficacy of Fractional Nd:YAG Laser Therapy Alone vs. Combination Approaches
Peer-Reviewed Journal (SCIE/SCOPUS Indexed) – 2020
This comparative study evaluated fractional Nd:YAG laser monotherapy against combination modality protocols for the treatment of pigmentation and skin quality concerns. While fractional Nd:YAG alone produced clinically meaningful results, combination approaches delivered superior outcomes in melanin reduction and texture improvement.
A Comparative Study of the Efficacy of Fractional Nd:YAG Laser Therapy Alone vs. Combination Approaches
Peer-Reviewed Journal (SCIE/SCOPUS Indexed) – 2020
This comparative study evaluated fractional Nd:YAG laser monotherapy against combination modality protocols for the treatment of pigmentation and skin quality concerns. While fractional Nd:YAG alone produced clinically meaningful results, combination approaches delivered superior outcomes in melanin reduction and texture improvement.
Helios Clinical Paper Summary — Comprehensive Evidence Overview
Helios Internal Clinical Summary – 2020
This internal summary document collates the principal clinical evidence supporting the Helios platform across its key indications: tattoo removal, pigmentation, skin rejuvenation, and fungal conditions. It provides practitioners with a consolidated reference point for understanding the clinical breadth of the Q-switched Nd:YAG laser platform.
Helios Clinical Paper Summary — Comprehensive Evidence Overview
Helios Internal Clinical Summary – 2020
This internal summary document collates the principal clinical evidence supporting the Helios platform across its key indications: tattoo removal, pigmentation, skin rejuvenation, and fungal conditions. It provides practitioners with a consolidated reference point for understanding the clinical breadth of the Q-switched Nd:YAG laser platform.
Mycosis Treatment with the Helios II Laser System
Helios Clinical White Paper – 2020
This white paper details the use of the Helios II Q-switched Nd:YAG laser system for the treatment of superficial mycosis. The laser's wavelength-specific penetration enabled effective targeting of fungal colonies in nail and surrounding tissue, providing an adjunctive non-pharmacological treatment option for this difficult-to-manage condition.
Onychomycosis Treatment Using the Helios II Laser System
Helios Clinical White Paper – 2020
This paper evaluates the Helios II laser in the specific context of onychomycosis (fungal nail infection). Patients who completed the full treatment protocol showed measurable improvement in nail clarity and reduction in fungal load, with the laser offering a safe and well-tolerated alternative to oral antifungals.
Onychomycosis Treatment Using the Helios II Laser System
Helios Clinical White Paper – 2020
This paper evaluates the Helios II laser in the specific context of onychomycosis (fungal nail infection). Patients who completed the full treatment protocol showed measurable improvement in nail clarity and reduction in fungal load, with the laser offering a safe and well-tolerated alternative to oral antifungals.
Laser Skin Rejuvenation with Fractional 1064 Q-Switched Nd:YAG in 252 Patients
Peer-Reviewed Journal (SCIE/SCOPUS Indexed) – 2019
This large-cohort study followed 252 patients treated with fractional 1064 nm Q-switched Nd:YAG laser for skin rejuvenation. Outcomes included significant improvement in overall skin tone, pore size, and superficial pigmentation, with an acceptable safety profile across Fitzpatrick types II–V.
Laugier-Hunziker Syndrome: Complete Clearance of Mucosal Lentigines
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2019
This clinical report documents complete clearance of mucosal pigmented lesions in a patient diagnosed with Laugier-Hunziker syndrome, a rare benign condition causing pigmentation of the lips and oral mucosa. Q-switched Nd:YAG laser treatment achieved full clearance with no recurrence at the reported follow-up period.
Effects of Picosecond Laser on Multicoloured Tattoo Removal Using Hartley Guinea Pig Model
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2018
This pre-clinical study used the Hartley guinea pig model to evaluate the effectiveness of picosecond laser pulses on multicoloured tattoo ink removal. The picosecond delivery produced superior ink particle fragmentation compared to nanosecond controls, particularly for difficult-to-clear pigments such as green and blue, laying groundwork for clinical application in multi-ink tattoo removal.
Effects of Picosecond Laser on Multicoloured Tattoo Removal Using Hartley Guinea Pig Model
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2018
This pre-clinical study used the Hartley guinea pig model to evaluate the effectiveness of picosecond laser pulses on multicoloured tattoo ink removal. The picosecond delivery produced superior ink particle fragmentation compared to nanosecond controls, particularly for difficult-to-clear pigments such as green and blue, laying groundwork for clinical application in multi-ink tattoo removal.
Combined Vitamin C Sonophoresis and Nd:YAG Laser for Facial Hyperpigmentation
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2016
This study tested the combination of topical vitamin C delivered via sonophoresis alongside Q-switched Nd:YAG laser sessions for facial hyperpigmentation. The combined approach produced greater reduction in melanin index scores than either treatment alone, suggesting a synergistic effect between laser-based disruption and antioxidant-assisted pigment clearance.
Combined Vitamin C Sonophoresis and Nd:YAG Laser for Facial Hyperpigmentation
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2016
This study tested the combination of topical vitamin C delivered via sonophoresis alongside Q-switched Nd:YAG laser sessions for facial hyperpigmentation. The combined approach produced greater reduction in melanin index scores than either treatment alone, suggesting a synergistic effect between laser-based disruption and antioxidant-assisted pigment clearance.
Using a Low-Fluence Q-Switched 532/1064 nm Nd:YAG Laser for Facial Skin Depigmentation
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2016
This study tested the efficacy of a low-fluence, multi-pass Q-switched protocol at both 532 nm and 1064 nm wavelengths for overall facial skin depigmentation and rejuvenation. The toning approach, using subthreshold energy across multiple passes, proved effective for diffuse pigmentation and overall skin brightening without the downtime of higher-fluence ablative protocols.
Using a Low-Fluence Q-Switched 532/1064 nm Nd:YAG Laser for Facial Skin Depigmentation
Peer-Reviewed Dermatology Journal (SCIE/SCOPUS Indexed) – 2016
This study tested the efficacy of a low-fluence, multi-pass Q-switched protocol at both 532 nm and 1064 nm wavelengths for overall facial skin depigmentation and rejuvenation. The toning approach, using subthreshold energy across multiple passes, proved effective for diffuse pigmentation and overall skin brightening without the downtime of higher-fluence ablative protocols.
Successful Treatment of Refractory Melasma Using Invasive Micro-Pulsed Electric Stimulation
Aesthetic Dermatology Journal – 2015
This study addressed the challenge of refractory melasma — cases that have not responded to conventional topical or laser approaches — using a micro-pulsed technique. The protocol produced notable lightening of resistant melasma patches with manageable recovery, offering an option for patients who have failed prior treatment lines.
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Noon Aesthetics
The Efficacy and Safety of NOON’s Patented DermShield Technology: A Clinical Evaluation
Journal of Drugs in Dermatology (JDD) – 2021
This peer-reviewed study, published in the Journal of Drugs in Dermatology, evaluated the efficacy and tolerability of NOON DermShield across a patient cohort with compromised skin barrier function. Results confirmed the formulation's protective and regenerative properties, with statistically significant improvement in transepidermal water loss (TEWL) measurements and patient-reported skin comfort scores.
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ReadyMedical
ReadyMedical ANTIOXIDANT VIT C – Antioxidant activity In-Vitro Test by the University of Pavia, Italy
BIO BASIC Laboratories Independent Testing – 2019
This independent laboratory study evaluated the antioxidant activity of ReadyMedical ANTIOXIDANT VIT C on irradiated human keratinocytes. Results show that even at low concentrations of 0.0156 mg/ml, the product provides a remarkable protection of irradiated skin cells, with 75% more ROS reduction compared to the study control
ReadyMedical ANTIOXIDANT VIT C – Antioxidant activity In-Vitro Test by the University of Pavia, Italy
BIO BASIC Laboratories Independent Testing – 2019
This independent laboratory study evaluated the antioxidant activity of ReadyMedical ANTIOXIDANT VIT C on irradiated human keratinocytes. Results show that even at low concentrations of 0.0156 mg/ml, the product provides a remarkable protection of irradiated skin cells, with 75% more ROS reduction compared to the study control
ReadyMedical ACNYCID – Anti-Inflammatory In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2018
This independent laboratory study evaluated the anti-inflammatory activity of ReadyMedical ACNYCID on Acne-stimulated human keratinocytes. Results show a significant 39%-41% reduction of inflammatory markers, 8h after treatment
ReadyMedical ACNYCID – Anti-Inflammatory In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2018
This independent laboratory study evaluated the anti-inflammatory activity of ReadyMedical ACNYCID on Acne-stimulated human keratinocytes. Results show a significant 39%-41% reduction of inflammatory markers, 8h after treatment
ReadyMedical ACNYCID – Antibacterial In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2018
This independent laboratory study evaluated the inhibition of C. Acne bacterial growth after treatment with ReadyMedical ACNYCID. Results show a significant 99.9% reduction of bacterial growth after 6h and 24h of treatment.
ReadyMedical POST-TREATMENT – Anti-Inflammatory In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2017
This independent laboratory study evaluated the anti-inflammatory activity of ReadyMedical ACNYCID on stimulated human fibroblasts. Results show a highly significant 94% reduction of inflammatory markers, 24h after treatment
ReadyMedical REVITALIZING PEPTIDES – Cell Proliferation In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2017
This independent laboratory study evaluated the cell proliferation and wound healing activity of ReadyMedical REVITALIZING PEPTIDES on stimulated human fibroblasts. Results show a significant 44% increase in cell motility and viability, 48h after treatment.
ReadyMedical REVITALIZING PEPTIDES – Cell Proliferation In-Vitro Test by the University of Pavia, Italy
UB-CARE Laboratories Independent Testing – 2017
This independent laboratory study evaluated the cell proliferation and wound healing activity of ReadyMedical REVITALIZING PEPTIDES on stimulated human fibroblasts. Results show a significant 44% increase in cell motility and viability, 48h after treatment.
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